The Gold Standard in Dermatology
Tretinoin (all-trans retinoic acid) is a highly potent prescription retinoid. It is clinically recognized as the gold standard for treating photoaging, fine lines, acne, and uneven skin texture.
How Retinoic Acid Rejuvenates Skin cells
Tretinoin works by interacting directly with retinoid receptors in your skin cell nucleus:
- Accelerated Cell Turnover: Speeds up your skin's natural shedding cycle from 28 days to roughly 14 days, clearing dead skin and unclogging pores.
- Collagen Synthesis: Stimulates fibroblasts to produce new collagen and elastin fibers, increasing skin thickness and elasticity.
The Top Vetted Dermatological Telehealth Brands of 2026
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Hers
- Offerings: Customized prescription skincare creams containing tretinoin, azelaic acid, and niacinamide built for women's skin.
- Hers Brand Page & Review
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Hims
- Offerings: Custom compounded anti-aging and acne creams containing dermatologist-selected levels of active tretinoin.
- Hims Brand Page & Review
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Wisp
- Offerings: Quick, convenient prescription consultations and custom topical formulas delivered directly to your home.
- Wisp Brand Page & Review